Is warm ischemia not a risk factor for delayed graft function in a living-donor kidney transplant?

نویسندگان

  • Taqi T Khan
  • Faheem Akhtar
  • Basem Koshaji
چکیده

The association between prolonged donor warm ischemia time and poor early graft function has been challenged, but with little evidence. We intend to remove ambiguities and present evidence from the current literature. All donor surgeons must strive to limit warm ischemia to reduce poor early graft function and improve long-term outcomes.

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Effect of Hypertonic Saline 5% on Early Graft Function and Urinary Interleukin 18 and Neutrophil Gelatinase-Associated Lipocalin in Deceased-Donor Kidney Transplantation

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Effect of Hypertonic Saline 5% on Early Graft Function and Urinary Interleukin 18 and Neutrophil Gelatinase-Associated Lipocalin in Deceased-Donor Kidney Transplantation

Ischemia reperfusion injury (IRI) is one of the main causes of delay graft function (DGF) in deceased-donor kidney transplantation (DDKT). Evidences suggest that hypertonic saline (HS) has beneficial effects on IRI. The objective of the present study is to determine the effect of intraoperative HS, on graft function and urinary biomarkers of interleukin 18 (IL-18) and neutrophil gelatinase-asso...

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Background & Aims: Delayed graft function (DGF) is an important challenge in the field of kidney transplantation. Occurrence of DGF is associated with low 1st-and 5thyear graft survival rate. Reducing the incidence of DGF minimizes financial burden on the health care system and improves the quality of life for organ recipients. Although over 2000 transplantations have been performed in Imam Kha...

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عنوان ژورنال:
  • Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

دوره 11 6  شماره 

صفحات  -

تاریخ انتشار 2013